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Misdiagnosis of Deep Vein Thrombosis (DVT) After Venaseal Procedure: A Growing Concern for General Practitioners

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The Venaseal procedure, a minimally invasive treatment for varicose veins, has gained popularity due to its efficacy and reduced recovery time. This procedure involves the use of a medical adhesive to close the affected veins. Despite its advantages, the Venaseal procedure presents a unique diagnostic challenge: the potential misdiagnosis of Deep Vein Thrombosis (DVT). As general practitioners (GPs) on the frontline of patient care, it is crucial to understand this issue and its implications. Clinical Presentation and Diagnostic Challenges Patients who undergo the Venaseal procedure often present with symptoms that can mimic those of DVT, such as leg swelling, discomfort, and localized pain. These symptoms are typically a normal part of the post-procedural healing process but can raise concerns about possible DVT. This overlap in clinical presentation poses a significant diagnostic challenge. The primary concern is distinguishing between benign post-procedural changes and actual thrombotic events that require intervention. Diagnostic Tools and Considerations Ultrasound imaging is the gold standard for diagnosing DVT. However, after a Venaseal procedure, ultrasound can show changes that might be mistaken for thrombus, such as hyperechoic material within the vein. This material is the adhesive used in the procedure and not a thrombus, but its appearance can lead to misinterpretation. General practitioners must be aware of these imaging nuances and consider the recent procedural history when evaluating ultrasound results. Importance of Ultrasound in a Vascular Lab While ultrasound imaging is essential, performing these scans in a vascular lab, rather than by general radiologists, can significantly improve diagnostic accuracy. Vascular labs are staffed by specialists trained specifically in vascular imaging, who are more familiar with the subtleties of post-Venaseal appearances. Their expertise can help differentiate between adhesive-related changes and true thrombotic events more reliably, reducing the risk of misdiagnosis. Importance of Accurate Diagnosis Accurate diagnosis is crucial to avoid unnecessary anticoagulation therapy, which can lead to complications such as bleeding. Conversely, missing an actual DVT diagnosis can result in serious consequences, including pulmonary embolism. Therefore, a balanced approach is necessary. GPs should maintain a high index of suspicion for DVT but also recognize the context of recent Venaseal procedures. Recommendations for General Practitioners1. Thorough Patient History: Always take a detailed procedural history if a patient presents with symptoms suggestive of DVT. Knowing that a Venaseal procedure was recently performed can provide crucial context for interpreting symptoms and imaging results.2. Utilise Vascular Labs: Refer patients to vascular labs for ultrasound imaging when DVT is suspected post-Venaseal. Specialists in these labs are better equipped to distinguish between adhesive-related changes and actual thrombi.3. Patient Education: Inform patients about the expected post-procedural symptoms and the signs of DVT that warrant immediate medical attention. This education can help reduce anxiety and ensure timely reporting of concerning symptoms.4. Follow-Up Protocols: Implement follow-up protocols for patients who have undergone the Venaseal procedure. Regular check-ins can help monitor recovery and identify any complications early.ConclusionThe misdiagnosis of DVT following the Venaseal procedure is a pertinent issue for GPs. By understanding the unique challenges posed by this procedure and leveraging the expertise of vascular labs, GPs can improve diagnostic accuracy, enhance patient outcomes, and reduce the risk of unnecessary treatments. Awareness, collaboration, and patient education are key strategies in addressing this growing concern. As the use of the Venaseal procedure continues to rise, staying informed about its implications will be essential for effective primary care practice.


Dr Shannon D. Thomas BSc Med Hons, MBBS Hons, FRACS

Vascular and Endovascular Surgeon

Conjoint Senior Lecturer UNSW

Prince of Wales Hospital Randwick, NSWAUSTRALIA

 
 
 

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